中文名稱

膀胱腫瘤抗原

別名

補體因子H（Complement Factor H）是膀胱腫瘤抗原（Bladder Tumor Antigen, BTA）的具體成分，是由尿路上皮腫瘤細胞和巨噬細胞產生的，不是正常表皮細胞產生的

英文別名

BTA; complement factor H; complement factor H, isoform b; Factor H; factor H like 1; FH; FHL 1; FHL1; H factor 1 (complement); H factor 1; H factor 2 (complement); HF 1; HF 2; HF; HF1; HF2; HUS; MGC88246.  

性    狀

Lyophilized powder

多肽活性

多肽

產品來源

合成

純化方法

HPLC

產品應用

Blocking Peptide of The Antibody

保存條件

Store at -20 °C for one year.

產品介紹

This is one synthetic peptide derived from human Factor H.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011] Function : Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.